La complementariedad de censos y encuestas en la estimación de indicadores de soltería

Comunicació presentada al IV Congreso de la Asociación Latinoamericana de Población-ALAP: "Condiciones y transformaciones culturales. Factores económicos y tendencias demográficas en Latinoamérica". La Habana (Cuba), del 16 al 19 de novembre de 2010.A partir de la variable "estado civil" de los Censos de Población en Latinoamérica, se analiza el efecto que la disolución de las uniones consensuales tiene en los niveles de soltería. Para ello comparamos los datos censales con los de las Encuestas de Demografía y Salud (DHS), en aquellos países y años para los que disponemos de ambas fuentes (Bolivia, Brasil, Colombia y Perú). Los resultados muestran claramente que las proporciones de "nunca unidas", derivadas de la variable censal "estado civil", son sistemáticamente más elevadas que las estimadas a partir de las DHS. Esta sobreestimación obedece al hecho de que personas que estuvieron en unión libre en el pasado se declaran solteras en el momento del Censo. La elevada proporción de mujeres solteras que, según el Censo, tienen hijos, es una prueba de ello y a su vez una solución efectiva para corregir el sesgo.A partir de la variable "estat civil" dels Censos de Població Llatinoamericans, s'analitza l'efecte que la dissolució de les unions consensuals té en els nivells de solteria. Es comparen les dades censals amb les de les Enquestes de Demografia i Salut (DHS) en aquells països i anys per als que es disposen d'ambdues fonts (Bolívia, Brasil, Colòmbia i Perú). Els resultats mostren que les proporcions de "mai unides", derivades de la variable censal "estat civil", són sistemàticament més elevades que les estimades a partir de les DHS. Aquesta sobreestimació prové del fet que, persones que estaven en unió lliure en el passat, es declaren solteres en el moment del cens. L'elevada proporció de dones solteres que tenen fills, segons el Cens, és una prova d'això i, a la vegada, una solució efectiva per corregir el biaix.This paper investigates the effect of consensual union dissolution on the observed levels of women never in union as estimated from the marital status variable in Latin American population censuses. We compare census data with data from Demographic and Health Surveys (DHS) for those countries and years where both sources are available (Bolivia, Brazil, Colombia, and Peru). Results show that the proportions of women never in union based on the census 'marital status' variable are systematically higher than those estimated from the DHS. This overestimation is due to individuals formerly in consensual unions declaring themselves as single at the time of the census. The large proportion of single women that have children is strong evidence of this and at the same time appears to be a valid and practical option to correct the bias

TokenTLB+CUP: A Token-Based Page Classification with Cooperative Usage Prediction

[EN] Discerning the private or shared condition of the data accessed by the applications is an increasingly decisive approach to achieving efficiency and scalability in multi- and many-core systems. Since most memory accesses in both sequential and parallel applications are either private (accessed only by one core) or read-only (not written) data, devoting the full cost of coherence to every memory access results in sub-optimal performance and limits the scalability and efficiency of the multiprocessor. This paper introduces TokenTLB, a TLB-based page classification approach based on exchange and count of tokens. Token counting on TLBs is a natural and efficient way for classifying memory pages, and it does not require the use of complex and undesirable persistent requests or arbitration. In addition, classification is extended with Cooperative Usage Predictor (CUP), a token-based system-wide page usage predictor retrieved through TLB cooperation, in order to perform a classification unaffected by TLB size. Through cycle-accurate simulation we observed that TokenTLB spends 43.6% of cycles as private per page on average, and CUP further increases the time spent as private by 22.0%. CUP avoids 4 out of 5 TLB invalidations when compared to state-of-the-art predictors, thus proving far better prediction accuracy and making usage prediction an attractive mechanism for the first time.This work has been jointly supported by the MINECO and European Commission (FEDER funds) under the project TIN2015-66972-C5-1-R and TIN2015-66972-C5-3-R and the Fundacion Seneca-Agencia de Ciencia y Tecnologia de la Region de Murcia under the project Jovenes Lideres en Investigacion 18956/JLI/13.Esteve Garcia, A.; Ros Bardisa, A.; Robles Martínez, A.; Gómez Requena, ME. (2018). TokenTLB+CUP: A Token-Based Page Classification with Cooperative Usage Prediction. IEEE Transactions on Parallel and Distributed Systems. 29(5):1188-1201. https://doi.org/10.1109/TPDS.2017.2782808S1188120129

TLB-Based Temporality-Aware Classification in CMPs with Multilevel TLBs

"© 2017 IEEE. Personal use of this material is permitted. Permissíon from IEEE must be obtained for all other uses, in any current or future media, including reprinting/republishing this material for advertisíng or promotional purposes, creating new collective works, for resale or redistribution to servers or lists, or reuse of any copyrighted component of this work in other works."[EN] Recent proposals are based on classifying memory accesses into private or shared in order to process private accesses more efficiently and reduce coherence overhead. The classification mechanisms previously proposed are either not able to adapt to the dynamic sharing behavior of the applications or require frequent broadcast messages. Additionally, most of these classification approaches assume single-level translation lookaside buffers (TLBs). However, deeper and more efficient TLB hierarchies, such as the ones implemented in current commodity processors, have not been appropriately explored. This paper analyzes accurate classification mechanisms in multilevel TLB hierarchies. In particular, we propose an efficient data classification strategy for systems with distributed shared last-level TLBs. Our approach classifies data accounting for temporal private accesses and constrains TLB-related traffic by issuing unicast messages on first-level TLB misses. When our classification is employed to deactivate coherence for private data in directory-based protocols, it improves the directory efficiency and, consequently, reduces coherence traffic to merely 53.0%, on average. Additionally, it avoids some of the overheads of previous classification approaches for purely private TLBs, improving average execution time by nearly 9% for large-scale systems.This work has been jointly supported by the MINECO and European Commission (FEDER funds) under the project TIN2015-66972-C5-1-R and TIN2015-66972-C5-3-R and the Fundacion Seneca-Agencia de Ciencia y Tecnologia de la Region de Murcia under the project Jovenes Lideres en Investigacion 18956/JLI/13.Esteve Garcia, A.; Ros Bardisa, A.; Gómez Requena, ME.; Robles Martínez, A.; Duato Marín, JF. (2017). TLB-Based Temporality-Aware Classification in CMPs with Multilevel TLBs. IEEE Transactions on Parallel and Distributed Systems. 28(8):2401-2413. https://doi.org/10.1109/TPDS.2017.2658576S2401241328

Consumption of Alcohol, Cannabis, and Tobacco in a Cohort of Adolescents before and during COVID-19 Confinement

The aim of this study was to identify changes in the hazardous consumption of alcohol, tobacco, and cannabis, due to the COVID-19 lockdown in 2020 in a cohort of schooled adolescents from Central Catalonia. We also analyzed the effect of the individual and social factors on risky consumption during confinement. This longitudinal study involved a subsample of 303 adolescents aged 14-18 years, who were attending 4th year of compulsory secondary education (ESO), 2nd year of college preparation (baccalaureate), or Vocational and Educational Training (VET). We collected data before COVID-19 lockdown (October 2019-February 2020) and 2 months after the lockdown ended. We estimated the prevalence of risky substance use in the sample at baseline for each independent variable. We used Poisson regression models with robust variance to compute the Cumulative Incidence (CI) and Relative Risk (RR), with their respective 95% confidence interval. We found that VET students had a significantly (p < 0.05) higher risk of substance use: binge drinking (RR = 3.21 (95%CI: 1.00-10.34)); hazardous drinking of alcohol (RR = 3.75 (95%CI: 1.12-12.54)), hazardous consumption of cannabis (RR = 3.75 (95%CI: 0.65-21.59)) and daily smoking of tobacco (RR = 4.82 (95%CI: 1.74-13.39)). The results showed a general trend of reduction of consumption during COVID-19 confinement period. This study suggests that VET students were more likely to engage in hazardous drinking of alcohol and daily smoking of tobacco. No statistically significant differences were found for the other age groups and variables

Polystyrene nanoplastics target lysosomes interfering with lipid metabolism through the PPAR system and affecting macrophage functionalization

Altres ajuts: acords transformatius de la UABNanoplastics (NPs) are currently a main concern for environmental, animal and human health due to their potential to accumulate in different environmental compartments and provoke effects in living organisms. Nevertheless, neither these effects nor the interaction of NPs with the cellular machinery are well characterized, and only scattered information is available. In the present work, we focused on the interaction between NPs and fish cells, both intestinal cells and macrophages, in order to understand which cell organelles are targeted by polystyrene (PS)-NPs and how this could impact cell function. PS-NPs can pass through phospholipid membranes, entering cells via endocytosis, phagocytosis or passive transport. Once internalized, we found that PS-NPs co-localize with lysosomes but not with mitochondria. Moreover, using two types of fluorescent probe (HDCFDA and DHE) we demonstrated that NPs did not trigger the production of reactive oxygen species (ROS), which was corroborated by the fact that neither the oxidative consumption ratio (OCR) nor the extracellular acidification rate (ECAR) in mitochondrial respiration were altered. RNASeq data revealed clear interference by PS-NPs with lipid metabolism, peroxisomes and PPAR signaling. The M1/M2 balance critically determines tissue homeostasis when exposed to exogenous agents such as microorganisms or pollutants. Thus, the expression of different genes (il1β, tnfα, il6, il10, il12, cox2, mmp9, ppar a, b and g) was further assessed to characterize the macrophage phenotype M1 or M2, induced by PS-NPs. Overall, in this study we demonstrate that PS-NPs co-localize within lysosomes, both in macrophages and in intestinal cells of rainbow trout, but do not trigger ROS production nor alter mitochondrial respiration. In macrophages, PS-NPs modulate polarization towards the M2-like phenotype

20 anys de Catalunya a la Unió Europea

Aquest llibre aprofita la efemèride del vintè aniversari de la integració de Catalunya a la UE per analitzar l'impacte de les principals polítiques europees i la seva influència en l'evolució de les polítiques a nivell catalàEste libro aprovecha la efeméride del vigésimo aniversario de la integración de Cataluña en la UE para analizar el impacto de las principales políticas europeas y su influencia en la evolución de las políticas a nivel catalá

EPIdemiology of Surgery-Associated Acute Kidney Injury (EPIS-AKI) : Study protocol for a multicentre, observational trial

More than 300 million surgical procedures are performed each year. Acute kidney injury (AKI) is a common complication after major surgery and is associated with adverse short-term and long-term outcomes. However, there is a large variation in the incidence of reported AKI rates. The establishment of an accurate epidemiology of surgery-associated AKI is important for healthcare policy, quality initiatives, clinical trials, as well as for improving guidelines. The objective of the Epidemiology of Surgery-associated Acute Kidney Injury (EPIS-AKI) trial is to prospectively evaluate the epidemiology of AKI after major surgery using the latest Kidney Disease: Improving Global Outcomes (KDIGO) consensus definition of AKI. EPIS-AKI is an international prospective, observational, multicentre cohort study including 10 000 patients undergoing major surgery who are subsequently admitted to the ICU or a similar high dependency unit. The primary endpoint is the incidence of AKI within 72 hours after surgery according to the KDIGO criteria. Secondary endpoints include use of renal replacement therapy (RRT), mortality during ICU and hospital stay, length of ICU and hospital stay and major adverse kidney events (combined endpoint consisting of persistent renal dysfunction, RRT and mortality) at day 90. Further, we will evaluate preoperative and intraoperative risk factors affecting the incidence of postoperative AKI. In an add-on analysis, we will assess urinary biomarkers for early detection of AKI. EPIS-AKI has been approved by the leading Ethics Committee of the Medical Council North Rhine-Westphalia, of the Westphalian Wilhelms-University Münster and the corresponding Ethics Committee at each participating site. Results will be disseminated widely and published in peer-reviewed journals, presented at conferences and used to design further AKI-related trials. Trial registration number NCT04165369

The Rise of Cohabitation in Latin America and the Caribbean, 1970-2011

This chapter offers a general overview of the often spectacular rise of the share of cohabitation in the process of union formation in 24 Latin American and Caribbean countries during the last 30 years of the twentieth and the first decade of the twenty-first century. First, we offer a brief ethnographic and historical sketch to illustrate the special position of many Latin American regions and sub-populations with respect to forms of partnership formation other than classic marriage. Second, we present the national trends in the rising share of cohabitation in union formation for men and women for the age groups 25-29 and 30-34. Third, we inspect the education and social class differentials by presenting the cross-sectional gradients over time. Fourth, we reflect on the framework of the "second demographic transition" and hence on the de-stigmatization of a number of other behaviors that were equally subject to strong normative restrictions in the past (e.g. divorce, abortion, homosexuality, suicide and euthanasia). Last, we deal with the household and family contexts of married persons and cohabitors respectively